What Bipolar Does to the Brain

I’ve been researching what bipolar does to the brain and seriously—fuck.

There’s both a lot more research than my 25-year-old B.A. in Psychology could assimilate and not nearly enough. A layperson’s book on the subject is sorely needed.

Here’s the gist.

* There’s solid evidence that the dysfunction during depressive and manic states causes changes that persist into our baseline states.

* There are several neurotransmitters involved: dopamine, norepinephrine, serotonin, GABA (gamma-aminobutyrate), glutamate, and acetylcholine at the least. And hormones that act like neurotransmitters are in the mix, too, like endorphins and oxytocin.

* Brain structures yet discovered to be involved/affected include areas of the prefrontal and temporal lobes, the hippocampus, thalamus, and hypothalamus.

* Bipolar affects both grey and white matter, meaning both the structural elements of the brain and the connective tissue between them. And by affects, I mean corrodes over time.

There’s more—like how it impedes plasticity and neuroregeneration, and how it causes the brain’s immune system to malfunction—the point is made: it does a terrifying amount of damage.

And while psychiatry is throwing darts at a moving target (bless their souls), I’m going to take my brain health very seriously. What else is there to do?

Comments

Embrace the Cheese

Why is it so hard to be kind to ourselves—gentle, caring, compassionate—when inside and recovering from an episode? Because we are not who we grew up wanting to be, thinking we’d become. In that sense, we are failures. Because we are reminded every morning with that first pill that something is wrong with us, will always be wrong with us. Because we were taught to be strong women and men. We were taught that if we worked hard enough, were smart enough, we could do anything . Solve the problem! Pull yourself up by your bootstraps! “Pure Horatio Alger,” says Hunter Thompson, which should be our first clue if not our forty-seventh. It’s hard to be kind, gentle, compassionate, when our brains are incessantly tearing us down, trying to get us to give up, give all the way up. It’s hard not to believe your own brain. But we have to believe we deserve kindness and compassion from ourselves. It takes work. I’m certainly still working on it. It takes mindfulness and self-remembering...

Self-Care for Bipolar Depression

Similar to the list for Self-Carefor Hypomanic Episodes , this is the one I use for depression. Some entries are exactly the same, but they work differently here. Self-Care Strategies for Bipolar Depression Tell someone what’s going on. Verbalizing it makes it real and lets you know you’re not alone. Stick to the routine . The routine will get you out of bed. The routine will get you fed and showered. Let the routine take care of you. Try caffeine. If you aren’t addicted to caffeine and it still has the effect of giving you a little jolt, sometimes it can help. Be sure you aren’t in a mixed episode first though. Avoid stressors. Fuck em. Distract, distract, distract. My go-to is streaming. I save a few favorite shows for the shittiest of times. Some people find more comfort in rewatching. Maybe your go-to is music, drawing, reading, video games. Whatever you can hand your brain over to for safe keeping, do that. Limit social media. Funny memes? Sure. Doom scrolli...

Sleep

All of my life, nighttime has been my favorite time. I’m most at peace, most relaxed and myself at night, when the world has gone to bed. When there is no more work, no chores or errands, and the phone can safely be ignored. Loved ones sleep soundly, needing nothing from me, and I am free to write, to read, to watch old movies, to unwind completely, stay up late in the quiet dark, and simply be. But the number one signal/trigger of a bipolar episode is disturbed sleep. My respite has consequences. So now my sleep hygiene (such a Dr. Kellogg kind of term) is perfect. A good eight hours every night (drug induced if need be). No caffeine after three, if at all. No alcohol. No wild nights out. The choice is follow the routine or lose even more days to the disorder. Be good or else.

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